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Record-breaking heat wave grips western United States

A record early heat wave striking the western United States on Friday is a one-in-500-year event and almost certainly the result of human-caused climate change, experts say. The heat has been toppling records this week and is set to continue into the weekend across western cities while expanding eastward. Four locations in the desert area near the California-Arizona border registered 44.4 degrees Celsius on Friday, a US national record for March. The readings were recorded near Yuma and Martinez Lake in Arizona, and around Winterhaven and Ogilby in California. Read: Intense heatwave grips US, triggering record-breaking temperatures Already, 65 cities have recorded new March highs, ranging from Arizona and California to Idaho, Weather.com reported. Death Valley reached 40°C on Thursday, while typically cool and foggy San Francisco tied its historic March record at 29°C. In Colorado, skiers were seen hitting the slopes shirtless. The National Weather Service issued extreme heat warni...
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AstraZeneca's Tagrisso plus chemo approved by China for first-line cancer therapy

 China has approved the use of AstraZeneca's (AZN.L), opens new tab blockbuster cancer drug Tagrisso in combination with chemotherapy as a first line of treatment for adults with a type of advanced lung cancer, the company said on Wednesday. AstraZeneca said the approval by China's National Medical Products Administration (NMPA) was based on trials which showed that patients given the combination treatment lived without the disease getting worse longer than those given just Tagrisso. The median progression-free survival of patients treated with Tagrisso and chemotherapy was 25.5 months, 8.8 months more than those treated with just Tagrisso. The decision by China's National Medical Products Administration was supported by findings from a phase 3 trial demonstrating that Tagrisso plus chemotherapy reduced the risk of disease progression or death by 38% compared to Tagrisso alone, as assessed by investigators. This approval is significant for the treatment of EGFR-mutated lung cancer, particularly in China, where it provides another effective treatment option alongside Tagrisso monotherapy.

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At least 32 miners dead after bridge fails at cobalt site in southeast DR Congo

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