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11 teenagers wounded in mass shooting at birthday gathering in US state of Georgia

Eleven teenagers were wounded in a mass shooting at a birthday gathering in the US state of Georgia, with two of them in critical condition, media reports said on Monday. The shooting occurred around midnight during a “large gathering” at Carolyn Crayton Park in Macon, about 85 miles (137 kilometres) southeast of Atlanta, CBS News reported, citing the Bibb County Sheriff’s Office. The victims were four 18-year-old men, two 18-year-old women and five 17-year-old boys. An 18-year-old man and a 17-year-old boy remained in critical condition, while the other nine victims were stable. Bibb County Sheriff David Davis said the gathering appeared to be a birthday party that had originally been planned at another location before attendees moved to the park. Another group later arrived, and an argument between the two groups escalated into gunfire, Davis said. All 11 people wounded were part of the birthday gathering. No arrests had been made, and the investigation r...

AstraZeneca's Tagrisso plus chemo approved by China for first-line cancer therapy

 China has approved the use of AstraZeneca's (AZN.L), opens new tab blockbuster cancer drug Tagrisso in combination with chemotherapy as a first line of treatment for adults with a type of advanced lung cancer, the company said on Wednesday. AstraZeneca said the approval by China's National Medical Products Administration (NMPA) was based on trials which showed that patients given the combination treatment lived without the disease getting worse longer than those given just Tagrisso. The median progression-free survival of patients treated with Tagrisso and chemotherapy was 25.5 months, 8.8 months more than those treated with just Tagrisso. The decision by China's National Medical Products Administration was supported by findings from a phase 3 trial demonstrating that Tagrisso plus chemotherapy reduced the risk of disease progression or death by 38% compared to Tagrisso alone, as assessed by investigators. This approval is significant for the treatment of EGFR-mutated lung cancer, particularly in China, where it provides another effective treatment option alongside Tagrisso monotherapy.

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